Lesson 8.6.1
8.6.1 Brain chemicals in Parkinson's and depression Quiz: Pearson Edexcel Biology, Unit 8
20 questions
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Lesson 8.6.1, Brain chemicals in Parkinson's and depression: 20 multiple choice questions for the Pearson Edexcel Biology (9BI0), Unit 8: Grey Matter, written with Revision Ninja.
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The 20 questions
-
Which neurotransmitter is deficient in the brain of a Parkinson's disease patient?
- Dopamine
- Serotonin
- Noradrenaline
- Acetylcholine
-
Low levels of which neurotransmitter are most strongly linked to clinical depression?
- Endorphin
- Serotonin
- GABA
- Dopamine
-
Which brain region suffers loss of dopamine-producing neurones in Parkinson's disease?
- Hypothalamus
- Cerebellum
- Substantia nigra
- Medulla oblongata
-
Which symptom is a characteristic motor feature of Parkinson's disease?
- Memory loss
- Loss of vision
- Hyperactivity
- Muscle tremors
-
What molecule is administered to Parkinson's patients to increase brain dopamine levels?
- GABA
- Serotonin
- Tyrosine
- L-Dopa
-
Why is L-Dopa used instead of dopamine to treat Parkinson's disease?
- Restores lost neurones
- Crosses blood-brain barrier
- Prevents enzyme breakdown
- Works instantly
-
What is a key clinical limitation of treating Parkinson's disease with L-Dopa?
- Immediate total cure
- Complete receptor destruction
- Unstopped neurone degeneration
- Permanent dopamine overproduction
-
Which drug type increases synaptic serotonin concentrations to treat depression?
- Opiates
- Beta blockers
- Antihistamines
- SSRIs
-
How do SSRIs raise serotonin activity at a synapse?
- Blocks presynaptic reuptake
- Stimulates serotonin synthesis
- Increases postsynaptic receptors
- Destroys monoamine oxidase
-
What chemical change in the brain causes Parkinson's disease symptoms?
- Acetylcholine depletion
- Serotonin excess
- Glutamate buildup
- Dopamine deficiency
-
Which neurotransmitter is primarily linked with mood regulation and depression?
- GABA
- Acetylcholine
- Dopamine
- Serotonin
-
Loss of dopamine-producing neurones in the brain mainly affects which function?
- Thermoregulation
- Movement control
- Memory consolidation
- Light perception
-
SSRIs take several weeks to show therapeutic benefits mainly due to which process?
- Neural adaptation
- Enzyme inhibition
- Rapid drug excretion
- Slow gut absorption
-
Which brain region shows reduced dopamine levels in patients with Parkinson's disease?
- Corpus callosum
- Cerebral cortex
- Medulla oblongata
- Substantia nigra
-
What type of molecule is serotonin in the human central nervous system?
- Hormone
- Enzyme
- Neurotransmitter
- Structural protein
-
How do dopamine receptor antagonists affect Parkinson's disease symptoms?
- Relieve symptoms
- Worsen symptoms
- No effect
- Cure disease
-
Which drug precursor is administered to treat dopamine deficiency in Parkinson's disease?
- L-Dopa
- MDMA
- Aspirin
- Tryptophan
-
Which neurotransmitter deficiency causes the motor symptoms seen in Parkinson's disease?
- Dopamine
- Serotonin
- Noradrenaline
- GABA
-
Parkinson's disease is primarily caused by the loss of neurones producing which neurotransmitter?
- Glutamate
- Acetylcholine
- Dopamine
- Serotonin
-
If a patient loses 60% of their 1000 dopamine neurones, how many remain?
- 60
- 600
- 400
- 40
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