Lesson 2.5.2

2.5.2 Cystic fibrosis and the gaseous exchange, digestive and reproductive systems Quiz: Pearson Edexcel Biology, Unit 2

20 questions

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Lesson 2.5.2, Cystic fibrosis and the gaseous exchange, digestive and reproductive systems: 20 multiple choice questions for the Pearson Edexcel Biology (9BI0), Unit 2: Genes and Health, written with Revision Ninja.

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The 20 questions

  1. What is the main effect of thick mucus in the lungs of cystic fibrosis patients?

    • Collapses alveoli
    • Blocks airways
    • Destroys cilia
    • Inhibits surfactant
  2. Why can digestive enzymes not reach the small intestine in cystic fibrosis?

    • Pancreatic ducts blocked
    • Bile duct damaged
    • Stomach acid neutralised
    • Gallbladder removed
  3. What causes infertility in most males with cystic fibrosis?

    • Damaged seminiferous tubules
    • Non-motile sperm
    • Absent prostate gland
    • Blocked vas deferens
  4. What prevents sperm from passing into the uterus in females with cystic fibrosis?

    • Lack of oestrogen
    • Thick cervical mucus
    • Blocked fallopian tubes
    • Absence of ovaries
  5. Which human organ system is most directly damaged by recurrent lung infections in cystic fibrosis?

    • Circulatory system
    • Gaseous exchange system
    • Digestive system
    • Endocrine system
  6. Why does cystic fibrosis cause malabsorption of fats in the duodenum?

    • Lipase cannot enter
    • Bile production stops
    • Villi are destroyed
    • Stomach acid neutralised
  7. Which structures in the liver can become blocked by thick secretions in cystic fibrosis?

    • Hepatic veins
    • Hepatic arteries
    • Lymph vessels
    • Bile ducts
  8. Which three organ systems are primarily affected by a mutated CFTR protein?

    • Digestive, respiratory, reproductive
    • Digestive, nervous, reproductive
    • Digestive, endocrine, respiratory
    • Respiratory, immune, circulatory
  9. Which two digestive enzyme types cannot reach the duodenum when pancreatic ducts are blocked?

    • Amylases and maltases
    • Proteases and lactases
    • Lipases and sucrases
    • Lipases and proteases
  10. A man with CF is infertile. Which structure is most directly responsible for this?

    • The bronchioles
    • The cervix
    • The vas deferens
    • The duodenum
  11. Why do people with cystic fibrosis experience frequent lung infections?

    • Phagocytes are destroyed
    • Mucus traps bacteria
    • Cilia stop beating
    • Alveoli burst open
  12. What is the medical term for fatty, bulky stools caused by pancreatic insufficiency?

    • Constipation
    • Diarrhoea
    • Steatorrhoea
    • Dysentery
  13. How does thick mucus affect the action of ciliated epithelial cells in airways?

    • Destroys cell nuclei
    • Prevents ciliary movement
    • Stops ATP production
    • Increases cilia length
  14. Where are the non-functional CFTR channels located that cause pancreatic duct blockage?

    • Gallbladder wall cells
    • Stomach mucosal cells
    • Ileum villus cells
    • Duct epithelial cells
  15. What primary physical failure causes recurrent chest infections in cystic fibrosis?

    • Decreased surfactant production
    • Reduced phagocyte count
    • Thickened alveolar membrane
    • Impaired mucociliary clearance
  16. Into which part of the small intestine do pancreatic enzymes normally travel?

    • Colon
    • Ileum
    • Jejunum
    • Duodenum
  17. What condition causes intestinal blockage in newborns with cystic fibrosis?

    • Hirschsprung disease
    • Meconium ileus
    • Pyloric stenosis
    • Intussusception
  18. Which main factor reduces fertility in females with cystic fibrosis?

    • Blocked fallopian tubes
    • Irregular ovulation cycles
    • Thick cervical mucus
    • Uterine fibroid growth
  19. Why is sweat chloride concentration abnormally high in people with cystic fibrosis?

    • Decreased sodium excretion
    • Increased water reabsorption
    • Increased chloride secretion
    • Reduced chloride reabsorption
  20. Why do cystic fibrosis patients take pancreatic enzyme supplements with meals?

    • Stimulation of insulin
    • Digestion of nutrients
    • Absorption of oxygen
    • Inhibition of mucus

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