Lesson 2.4.1
2.4.1 DNA replication and the Meselson and Stahl experiment Quiz: Pearson Edexcel Biology, Unit 2
20 questions
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Lesson 2.4.1, DNA replication and the Meselson and Stahl experiment: 20 multiple choice questions for the Pearson Edexcel Biology (9BI0), Unit 2: Genes and Health, written with Revision Ninja.
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The 20 questions
-
In semi-conservative replication, each new DNA molecule consists of what?
- Two original strands
- One original strand
- Two new strands
- Dispersed original fragments
-
Which heavy isotope was used to label original bacterial DNA in Meselson and Stahl's experiment?
- Nitrogen-14
- Nitrogen-15
- Phosphorus-32
- Carbon-14
-
Which enzyme joins free nucleotides to form a new DNA strand during replication?
- DNA ligase
- RNA polymerase
- DNA helicase
- DNA polymerase
-
Which enzyme breaks hydrogen bonds between complementary base pairs during DNA replication?
- DNA ligase
- DNA helicase
- DNA polymerase
- RNA primase
-
In which direction does DNA polymerase synthesise a new DNA strand?
- 3' to 5'
- 5' to 5'
- 3' to 3'
- 5' to 3'
-
How is the lagging strand synthesised during DNA replication?
- Discontinuously
- Dispersively
- Conservatively
- Continuously
-
Which base pairs with adenine in a DNA molecule?
- Uracil
- Guanine
- Cytosine
- Thymine
-
Bacteria with 15N DNA replicate once in 14N medium. What density band is observed?
- Intermediate density
- Two separate bands
- Heavy density
- Light density
-
Bacteria with 15N DNA replicate twice in 14N medium. Which bands are observed?
- Light only
- Heavy and light
- Intermediate and light
- Intermediate and heavy
-
A single double-stranded DNA molecule labelled with 15N is replicated for three generations in 14N. How many of the resulting molecules contain some 15N?
- 1 molecule
- 4 molecules
- 8 molecules
- 2 molecules
-
A DNA molecule labelled with 15N is replicated for four generations in 14N medium. What percentage of the resulting double-stranded molecules is entirely 14N?
- 87.5%
- 25%
- 12.5%
- 50%
-
Which DNA replication model was ruled out by obtaining a single intermediate density band?
- Conservative
- Dispersive
- Semi-conservative
- Continuous
-
The appearance of a light density band in generation two rules out which replication model?
- Semicontinuous
- Conservative
- Dispersive
- Semi-conservative
-
A DNA sample contains 30% adenine. What percentage of its bases is cytosine?
- 40%
- 10%
- 30%
- 20%
-
Which enzyme joins Okazaki fragments together on the lagging strand?
- RNA primase
- DNA polymerase
- DNA ligase
- DNA helicase
-
Why does DNA polymerase require a primer to start synthesising DNA?
- Requires free 3' end
- Unwinds the helix
- Requires free 5' end
- Breaks hydrogen bonds
-
A segment of 100 base pairs contains 40 G-C pairs and 60 A-T pairs. How many hydrogen bonds hold the segment together?
- 260
- 240
- 200
- 300
-
Which enzyme synthesises the short RNA primer needed to start DNA replication?
- Helicase
- Topoisomerase
- DNA ligase
- Primase
-
Why is the lagging strand synthesised in short fragments?
- Helicase stops frequently
- Strands are antiparallel
- Ligase works slowly
- Strands are parallel
-
What density bands would conservative replication produce after one generation in 14N medium?
- Heavy only
- Intermediate only
- Heavy and light
- Light only
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