Lesson 2.3.2
2.3.2 Globular and fibrous proteins: haemoglobin and collagen Quiz: Pearson Edexcel Biology, Unit 2
20 questions
In partnership with Revision Ninja
Lesson 2.3.2, Globular and fibrous proteins: haemoglobin and collagen: 20 multiple choice questions for the Pearson Edexcel Biology (9BI0), Unit 2: Genes and Health, written with Revision Ninja.
Host it live on the board and students join with a game code on their own devices, or revise alone with Free Play. The answers are revealed in the game.
The 20 questions
-
Which ion within the haem group of haemoglobin binds directly to oxygen?
- Magnesium ion
- Calcium ion
- Iron ion
- Sodium ion
-
How many polypeptide subunits does a normal adult haemoglobin molecule contain?
- 3
- 1
- 4
- 2
-
Why is haemoglobin soluble in aqueous cell cytoplasm?
- Insoluble cross-links
- Hydrophobic outer R-groups
- Triple helix structure
- Hydrophilic outer R-groups
-
Which structural feature gives collagen its high tensile strength?
- Triple helix
- Beta pleated sheet
- Single strand
- Alpha helix
-
Which amino acid is found at every third position in collagen's repeating sequence, allowing the three chains to pack closely?
- Haem
- Glycine
- Glutamate
- Cysteine
-
Which property of collagen's surface structure makes it insoluble in water?
- Hydrophilic outer regions
- Hydrophobic outer regions
- Ester cross-links
- Ionic surface bonds
-
Which human tissues contain a high proportion of collagen for tensile strength?
- Tendons and skin
- Brain and spinal cord
- Blood and plasma
- Alveoli and arteries
-
What is the main function of the prosthetic haem group in haemoglobin?
- ATP hydrolysis
- Structural rigidity
- Irreversible oxygen binding
- Reversible oxygen binding
-
What happens to haemoglobin's oxygen affinity after the first oxygen molecule binds?
- Oxygen affinity increases
- Subunits unfold completely
- Haem groups detach
- Oxygen affinity decreases
-
What effect does a decrease in pH have on haemoglobin's affinity for oxygen?
- Affinity fluctuates randomly
- Affinity stays constant
- Affinity decreases
- Affinity increases
-
Which amino acid substitution at position 6 causes sickle cell anaemia?
- Glutamate to valine
- Alanine to lysine
- Glycine to leucine
- Valine to glutamate
-
Why does replacing glutamate with valine cause haemoglobin molecules to aggregate?
- Forms covalent cross-links
- Creates hydrophilic patch
- Creates hydrophobic patch
- Breaks peptide bonds
-
Which structural feature is characteristic of fibrous proteins such as collagen?
- Hydrophilic outer surface
- Spherical tertiary shape
- Dynamic tertiary folding
- Repetitive amino acids
-
Which bonds between collagen molecules provide high tensile strength in tendons?
- Ionic bonds only
- Hydrogen bonds only
- Covalent cross-links
- Hydrophobic interactions
-
What is the general solubility of fibrous proteins in water?
- Soluble in water
- Insoluble in water
- Reactive in water
- Hydrophilic throughout
-
How does a high carbon dioxide concentration affect the haemoglobin oxygen dissociation curve?
- Does not change position
- Removes the sigmoidal shape
- Shifts to the right
- Shifts to the left
-
Which structural level of haemoglobin refers to its four interconnected polypeptide chains?
- Quaternary structure
- Primary structure
- Secondary structure
- Tertiary structure
-
What is the main function of proline and hydroxyproline residues in collagen?
- Stabilising triple helix
- Binding oxygen reversibly
- Lowering activation energy
- Forming globular folds
-
What is the characteristic shape of haemoglobin's oxygen dissociation curve?
- Parabolic
- Sigmoidal
- Linear
- Hyperbolic
-
Which of these is a fibrous protein found in hair and nails?
- Keratin
- Amylase
- Insulin
- Haemoglobin
Related quizzes
- Gas exchange surfaces and Fick's Law Quiz · 2.1.1 · 20 questions
- Cell membrane structure and the fluid mosaic model Quiz · 2.1.2 · 20 questions
- Osmosis, diffusion and membrane transport Quiz · 2.1.3 · 20 questions
- Nucleotides, DNA and RNA structure Quiz · 2.2.1 · 20 questions
- Transcription, translation, the genetic code and genes Quiz · 2.2.2 · 20 questions
- Amino acids, polypeptides and protein structure Quiz · 2.3.1 · 20 questions
- Enzyme mechanism, specificity and activation energy Quiz · 2.3.3 · 20 questions
- DNA replication and the Meselson and Stahl experiment Quiz · 2.4.1 · 20 questions
- Mutations and cystic fibrosis Quiz · 2.4.2 · 20 questions
- Monohybrid inheritance and pedigree diagrams Quiz · 2.5.1 · 20 questions