Lesson 7.6.1

7.6.1 Transcription factors and hormones switching genes on and off Quiz: Pearson Edexcel Biology, Unit 7

20 questions

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Lesson 7.6.1, Transcription factors and hormones switching genes on and off: 20 multiple choice questions for the Pearson Edexcel Biology (9BI0), Unit 7: Run for your Life, written with Revision Ninja.

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The 20 questions

  1. What is the main function of a transcription factor in a cell?

    • Synthesising ATP
    • Translating mRNA
    • Regulating gene expression
    • Replicating DNA
  2. Which molecule is directly produced during the process of gene transcription?

    • Messenger RNA
    • Ribosomal RNA
    • Transfer RNA
    • Polypeptide chain
  3. Why can steroid hormones easily pass through cell-surface membranes?

    • Charged molecules
    • Lipid-soluble
    • Large proteins
    • Hydrophilic
  4. Where are receptors for steroid hormones located within a target cell?

    • Outer mitochondrial membrane
    • Ribosomes
    • Cell-surface membrane
    • Cytoplasm or nucleus
  5. Why must peptide hormones bind to receptors on cell-surface membranes?

    • Lipid-insoluble
    • Non-polar substances
    • Small molecules
    • Lipid-soluble
  6. What is the direct effect of a steroid hormone-receptor complex binding to DNA?

    • Blocked translation initiation
    • Accelerated DNA replication
    • Altered transcription rate
    • Increased phospholipid synthesis
  7. Which process immediately follows a lipid-soluble hormone entering a target cell?

    • Receptor binding
    • DNA binding
    • Exocytosis
    • Translation
  8. What type of transcription factor reduces the rate of mRNA synthesis?

    • Operon
    • Repressor
    • Promoter
    • Activator
  9. A 4-fold increase in mRNA after hormone treatment indicates an increase in what process?

    • Translation
    • Phosphorylation
    • Transcription
    • DNA replication
  10. Which of these lipid-soluble hormones acts as a transcription factor by binding intracellular receptors?

    • Glucagon
    • Oestrogen
    • Adrenaline
    • Insulin
  11. Which term describes the synthesis of functional products from information encoded in genes?

    • Somatic mutation
    • Gene expression
    • DNA replication
    • Genetic screening
  12. Why do only specific target cells respond to a particular steroid hormone?

    • Fast diffusion rate
    • Specific receptors present
    • Cell wall presence
    • High lipid solubility
  13. What chemical class of biological molecule comprises all transcription factors?

    • Steroids
    • Carbohydrates
    • Lipids
    • Proteins
  14. Why can the same steroid hormone produce different effects in different target cells?

    • Variable cell pH
    • Hormone structure changes
    • Different DNA sequences
    • Different genes expressed
  15. What relationship exists between hormone concentration and transcription rate when higher concentration increases transcription?

    • Positive correlation
    • No relationship
    • Inverse proportion
    • Negative correlation
  16. Where are receptors for non-steroid, protein-based hormones located in target cells?

    • Cell surface membrane
    • Nuclear matrix
    • Cytoplasm
    • Nucleolus
  17. What enables cells with identical genomes to differentiate into distinct specialised cell types?

    • Gene mutation rates
    • Cytoplasmic cleavage
    • DNA sequence variation
    • Selective gene transcription
  18. What effect does a drug blocking a transcription factor from DNA have on gene expression?

    • DNA degradation
    • Gene amplification
    • Increased translation
    • Reduced transcription
  19. Where are receptors for lipid-soluble steroid hormones typically located inside target cells?

    • Ribosomal subunit
    • Cell membrane exterior
    • Cytoplasm or nucleus
    • Glycocalyx
  20. What type of hormone diffuses into cells to form a functional transcription factor complex?

    • Peptide hormone
    • Steroid hormone
    • Protein hormone
    • Amine hormone

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