Lesson 8.7.2
8.7.2 Drugs produced by genetically modified organisms Quiz: Pearson Edexcel Biology, Unit 8
20 questions
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Lesson 8.7.2, Drugs produced by genetically modified organisms: 20 multiple choice questions for the Pearson Edexcel Biology (9BI0), Unit 8: Grey Matter, written with Revision Ninja.
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The 20 questions
-
Which organism is commonly genetically modified to produce human insulin?
- Agrobacterium tumefaciens
- Saccharomyces cerevisiae
- Escherichia coli
- Thermus aquaticus
-
What is a major advantage of using genetically modified bacteria to produce pharmaceutical proteins?
- High production cost
- Complex protein folding
- Rapid reproduction rate
- Splicing of introns
-
What technology is used to combine human genes with bacterial DNA to produce drugs?
- Gel electrophoresis
- Polymerase chain reaction
- Western blotting
- Recombinant DNA technology
-
Which vector is commonly used to transfer human genes into bacterial host cells?
- Plasmid
- Bacteriophage
- Liposome
- Ribosome
-
Which human protein is produced in the milk of genetically modified transgenic goats?
- Haemoglobin
- Rhodopsin
- Antithrombin
- Insulin
-
Which GM plant species is widely used to produce pharmaceutical proteins and vaccines?
- Maize
- Tobacco
- Wheat
- Barley
-
What is an advantage of using GM plants instead of GM animals for drug production?
- Higher pathogen risk
- Complex nervous systems
- Lower production costs
- Faster animal growth
-
What function does an industrial fermenter provide during drug production using GM bacteria?
- High radiation levels
- Uncontrolled temperature
- Controlled growth conditions
- Direct gene insertion
-
Why is GM human insulin preferred over animal-derived insulin for treating diabetes?
- Shorter shelf life
- Higher production cost
- Lower purity levels
- Reduced immune response
-
A culture yields 2 g of protein per litre. How much protein is produced in a 500 L fermenter?
- 500 g
- 2000 g
- 1000 g
- 250 g
-
Which risk associated with GM microorganisms is minimised by biological containment?
- Enzyme denaturation
- Rapid osmotic lysis
- Cellular respiration failure
- Horizontal gene transfer
-
Which property of the genetic code allows GM bacteria to produce human proteins?
- It is universal
- It is degenerate
- It is triplet-based
- It is non-overlapping
-
Which technique is used to purify a target protein from a genetically modified organism culture?
- Chromatography
- DNA sequencing
- PCR
- Gel electrophoresis
-
What is the main ethical concern associated with producing drugs using transgenic animals?
- High production cost
- Horizontal gene transfer
- Low protein purity
- Animal welfare
-
Which organelle in a host bacterium synthesises human drug proteins during translation?
- Nucleolus
- Golgi apparatus
- Ribosome
- Plasmid
-
Why might a human drug derived from GM bacteria trigger an adverse immune reaction?
- Ribosome mutation
- Contaminating endotoxins
- Absence of DNA
- Excessive insulin levels
-
What causes unexpected immune reactions in humans taking therapeutic proteins produced by GM plants?
- Bacterial plasmids
- Incompatible glycosylation
- Viral capsids
- Denatured ribosomes
-
Which medical hormone was the first human protein commercially produced by GM E. coli?
- Insulin
- Adrenaline
- Thyroxine
- Glucagon
-
Which advantage makes GM microorganisms preferred over animal tissues for drug production?
- No purification needed
- Longer shelf life
- Higher yield
- Zero production cost
-
Which human hormone produced by GM bacteria is used to treat pituitary dwarfism?
- Oestrogen
- Aldosterone
- Human growth hormone
- Oxytocin
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