Lesson 8.1.3

8.1.3 Synapses and neurotransmitters Quiz: Pearson Edexcel Biology, Unit 8

20 questions

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Lesson 8.1.3, Synapses and neurotransmitters: 20 multiple choice questions for the Pearson Edexcel Biology (9BI0), Unit 8: Grey Matter, written with Revision Ninja.

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The 20 questions

  1. What is the fluid-filled gap between a presynaptic and postsynaptic neurone called?

    • Node of Ranvier
    • Synaptic cleft
    • Synaptic knob
    • Axon hillock
  2. Which neurotransmitter is released at human neuromuscular junctions?

    • GABA
    • Dopamine
    • Acetylcholine
    • Serotonin
  3. Which ion enters the presynaptic knob to trigger neurotransmitter release?

    • Sodium ions
    • Calcium ions
    • Chloride ions
    • Potassium ions
  4. Which enzyme breaks down acetylcholine in the synaptic cleft?

    • Choline acetyltransferase
    • Acetylcholinesterase
    • Monoamine oxidase
    • Sodium-potassium ATPase
  5. Why must neurotransmitters be rapidly broken down after binding to postsynaptic receptors?

    • Prevent continuous stimulation
    • Increase action potential
    • Prevent sodium influx
    • Stop vesicle formation
  6. What is the direction of impulse transmission across a chemical synapse?

    • Random direction
    • Postsynaptic to presynaptic
    • Presynaptic to postsynaptic
    • Bidirectional transmission
  7. A reflex arc contains three synapses. If each synapse delays transmission by 0.5 ms, what is the total delay?

    • 1.5 ms
    • 3.0 ms
    • 1.0 ms
    • 0.5 ms
  8. What is the effect of blocking acetylcholinesterase at a chemical synapse?

    • Continuous stimulation
    • Decreased neurotransmitter release
    • Immediate inhibition
    • Reduced depolarisation
  9. Which ion channel opens on the postsynaptic membrane when acetylcholine binds to its receptor?

    • Ligand-gated potassium channels
    • Voltage-gated sodium channels
    • Voltage-gated calcium channels
    • Ligand-gated sodium channels
  10. What process causes the delay in signal transmission across a chemical synapse?

    • Action potential propagation
    • Sodium ion influx
    • Axon myelination
    • Neurotransmitter diffusion
  11. Compared to chemical synapses, how do electrical synapses transmit nerve impulses?

    • Faster and bidirectionally
    • Slower and bidirectionally
    • Faster and unidirectionally
    • Slower and unidirectionally
  12. What change occurs in the postsynaptic membrane when an excitatory neurotransmitter binds?

    • Hyperpolarisation
    • Repolarisation
    • Depolarisation
    • Resting potential maintenance
  13. What is the main function of synaptic vesicles in a presynaptic neurone?

    • Pumping calcium ions
    • Storing neurotransmitters
    • Synthesising ATP
    • Binding neurotransmitters
  14. If 200 vesicles release 5000 neurotransmitter molecules each per second, how many total molecules are released?

    • 100 000
    • 1 000 000
    • 5 200
    • 10 000 000
  15. What is the direct role of calcium ions during synaptic transmission?

    • Repolarising presynaptic membrane
    • Triggering vesicle exocytosis
    • Breaking down neurotransmitters
    • Depolarising postsynaptic membrane
  16. How does an inhibitory neurotransmitter affect the postsynaptic membrane potential?

    • Causes depolarisation
    • Maintains threshold potential
    • Causes hyperpolarisation
    • Prevents repolarisation
  17. Which feature ensures unidirectional impulse transmission across a chemical synapse?

    • Enzymes throughout the axon
    • Vesicles in postsynaptic membrane
    • Neurotransmitters in blood vessels
    • Receptors postsynaptically only
  18. What happens if a drug mimics acetylcholine and resists breakdown at synapses?

    • Rapid calcium depletion
    • Blocked nerve impulses
    • Immediate synaptic fatigue
    • Continuous postsynaptic stimulation
  19. What general impact do chemical synapses have on neural conduction speed?

    • Has no effect
    • Slows conduction
    • Speeds conduction
    • Stops transmission
  20. On which structure are neurotransmitter receptors located at a chemical synapse?

    • Presynaptic membrane
    • Postsynaptic membrane
    • Synaptic vesicle
    • Synaptic cleft

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