Lesson 3.5.1

3.5.1 Genotype, environment, epigenetics and polygenic variation Quiz: Pearson Edexcel Biology, Unit 3

20 questions

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Lesson 3.5.1, Genotype, environment, epigenetics and polygenic variation: 20 multiple choice questions for the Pearson Edexcel Biology (9BI0), Unit 3: Voice of the Genome, written with Revision Ninja.

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The 20 questions

  1. What term describes the observable physical characteristics of an organism?

    • Karyotype
    • Phenotype
    • Genotype
    • Allele
  2. Which term describes a trait controlled by multiple genes with a continuous distribution?

    • Monohybrid inheritance
    • Polygenic inheritance
    • Codominance
    • Sex linkage
  3. What alters gene expression without changing the underlying DNA base sequence?

    • Epigenetic modification
    • Chromosome translocation
    • Gene mutation
    • Nucleotide deletion
  4. What effect does DNA methylation usually have on the expression of a gene?

    • Inhibits expression
    • Translates protein
    • Increases transcription
    • Mutates DNA
  5. How does histone acetylation generally affect chromatin structure and gene transcription?

    • Inhibits translation
    • Promotes transcription
    • Prevents transcription
    • Degrades DNA
  6. What main factor causes phenotypic differences between genetically identical twins?

    • Chromosome deletions
    • Epigenetic differences
    • Karyotype changes
    • Different DNA sequences
  7. Which type of trait is controlled by many genes acting additively?

    • Sex-linked trait
    • Dominant trait
    • Monogenic trait
    • Polygenic trait
  8. What pattern of variation is shown by a polygenic trait in a large population?

    • Uniform distribution
    • Discontinuous variation
    • Bimodal distribution
    • Normal distribution
  9. Which factor can change an organism's phenotype without altering its genotype?

    • DNA replication error
    • Chromosomal translocation
    • Gene mutation
    • Environmental conditions
  10. What is the main function of epigenetic changes passed to daughter cells?

    • Induce genetic drift
    • Maintain gene expression
    • Cause DNA mutation
    • Increase chromosome number
  11. What type of variation results from alleles at many loci with small additive effects?

    • Sex-linked inheritance
    • Single-gene inheritance
    • Continuous variation
    • Discontinuous variation
  12. Which term describes the complete genetic makeup of an organism?

    • Genotype
    • Proteome
    • Phenotype
    • Epigenome
  13. Which environmental factor determines the flower colour variation seen in hydrangeas?

    • Chloroplast mutations
    • Polygenic inheritance
    • Epistatic alleles
    • Soil pH
  14. How are DNA methylation patterns maintained during cell division?

    • Randomly reassorted
    • Copied during replication
    • Erased completely
    • Doubled every cycle
  15. How do environmental factors alter phenotype without changing genotype?

    • Modifying gene expression
    • Deleting chromosomes
    • Mutating base sequences
    • Inserting new introns
  16. Which human characteristic is controlled by multiple genes acting polygenically?

    • Cystic fibrosis
    • Haemophilia
    • Skin colour
    • ABO blood group
  17. Which of these is an example of an environmental influence on human phenotype?

    • Eye colour
    • Blood type
    • Albinism
    • Skin scarring
  18. What term describes the full set of chemical modifications on an organism's DNA?

    • Epigenome
    • Transcriptome
    • Proteome
    • Genome
  19. What type of variation is produced by a single gene with discrete phenotype classes?

    • Polygenic variation
    • Epigenetic variation
    • Discontinuous variation
    • Continuous variation
  20. Why do environmental factors influence the phenotype of polygenic traits like height?

    • Altering amino acids
    • Changing DNA sequences
    • Altering gene expression
    • Inducing gene deletions

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