Lesson 4.1.1b

4.1.1b Non-specific defences and phagocytosis Quiz: OCR Biology, Unit 3

20 questions

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Lesson 4.1.1b, Non-specific defences and phagocytosis: 20 multiple choice questions for the OCR Biology (H020), Unit 3: Communicable diseases, disease prevention and the immune system, written with Revision Ninja.

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The 20 questions

  1. Which structure acts as a primary non-specific physical barrier against pathogens in animals?

    • B lymphocytes
    • Antibodies
    • Phagocytes
    • Skin
  2. Which cell fragments release substances that start the clotting cascade?

    • Platelets
    • Neutrophils
    • Red blood cells
    • Lymphocytes
  3. What insoluble protein forms a mesh during the blood clotting process?

    • Fibrin
    • Fibrinogen
    • Prothrombin
    • Thrombin
  4. Which type of white blood cell is the most abundant, and acts as a phagocyte?

    • Monocyte, a large phagocyte
    • Lymphocyte, a B or T cell
    • Platelet fragment
    • Neutrophil
  5. Which vesicle forms when a phagocyte engulfs a pathogen during phagocytosis?

    • Phagolysosome
    • Phagosome
    • Lysosome
    • Vacuole
  6. What role do lysosomes play during phagocytosis in a neutrophil?

    • Form blood clots
    • Produce specific antibodies
    • Release hydrolytic enzymes
    • Synthesise histamine
  7. Which chemicals released during inflammation attract phagocytes to the site of infection?

    • Clotting factors
    • Cytokines
    • Agglutinins
    • Antitoxins
  8. How do mucous membranes help defend the respiratory tract against pathogens?

    • Secreting histamine
    • Trapping pathogens
    • Ingesting bacteria
    • Producing antibodies
  9. Which enzyme converts soluble fibrinogen into insoluble fibrin during blood clotting?

    • Factor VIII
    • Thromboplastin
    • Prothrombin
    • Thrombin
  10. Which localised non-specific response causes redness, heat, and swelling at a wound?

    • Phagocytosis
    • Vaccination
    • Agglutination
    • Inflammation
  11. In which order do the main stages of phagocytosis occur?

    • Fusion, digestion, engulfment
    • Fusion, engulfment, digestion
    • Engulfment, fusion, digestion
    • Digestion, engulfment, fusion
  12. Which tough protein in the outer layer of skin acts as a physical barrier?

    • Fibrin
    • Collagen
    • Keratin
    • Elastin
  13. Which property makes coughing classified as a non-specific defence mechanism?

    • Responds to any irritant
    • Producing memory cells
    • Destroying infected cells
    • Targeting specific antigens
  14. Which cell fragment releases clotting factors to initiate the blood clotting cascade?

    • Monocytes
    • Platelets
    • Erythrocytes
    • Neutrophils
  15. Which shared cellular feature do both neutrophils and macrophages possess?

    • Produce antibodies
    • Secrete histamine
    • Perform phagocytosis
    • Form memory cells
  16. Why is the human inflammatory response described as a non-specific defence?

    • Involves specific antibodies
    • Produces clonal selection
    • Responds to any pathogen
    • Activates B lymphocytes
  17. What is the primary effect of a low blood platelet count on a wound?

    • Lower antibody production
    • Reduced phagocytosis
    • Slower blood clotting
    • Decreased histamine release
  18. What primary effect do cytokines released at a wound site have on phagocytes?

    • Destroy antigens
    • Attract them
    • Inhibit division
    • Digest them
  19. What is the primary role of antigen-presenting cells in the immune system?

    • Activating T cells
    • Releasing histamine
    • Producing antibodies
    • Engulfing erythrocytes
  20. Which term describes primary defences like skin, mucous membranes, and expulsive reflexes?

    • Non-specific barriers
    • Specific immune responses
    • Cell-mediated responses
    • Autoimmune reactions

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