Lesson 6.2.2

6.2.2 How TB and HIV infect human cells Quiz: Pearson Edexcel Biology, Unit 6

20 questions

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Lesson 6.2.2, How TB and HIV infect human cells: 20 multiple choice questions for the Pearson Edexcel Biology (9BI0), Unit 6: Immunity, Infection and Forensics, written with Revision Ninja.

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The 20 questions

  1. Which human immune cells are infected and inhabited by Mycobacterium tuberculosis?

    • Helper T cells
    • B lymphocytes
    • Macrophages
    • Neutrophils
  2. Which immune cells are primarily infected and destroyed by HIV?

    • B lymphocytes
    • Cytotoxic T cells
    • Helper T cells
    • Phagocytes
  3. Which viral glycoprotein on HIV binds to the CD4 receptor on host cells?

    • gp41
    • Haemagglutinin
    • Neuraminidase
    • gp120
  4. Which nucleic acid is produced by reverse transcriptase using viral RNA?

    • Protein
    • DNA
    • mRNA
    • tRNA
  5. Which enzyme inserts viral DNA into the host cell genome during HIV infection?

    • Reverse transcriptase
    • Integrase
    • RNA polymerase
    • DNA ligase
  6. Untreated HIV leads to opportunistic infections mainly due to the destruction of which cells?

    • Neutrophils
    • Red blood cells
    • B lymphocytes
    • Helper T cells
  7. Which structure is formed by immune cells around Mycobacterium tuberculosis in the lungs?

    • Granuloma
    • Biofilm
    • Plaque
    • Capsid
  8. Which symptom is a direct result of lung tissue damage in active tuberculosis?

    • Joint swelling
    • Loss of hearing
    • High blood pressure
    • Persistent cough
  9. Which enzyme allows HIV to convert its RNA genome into DNA?

    • Integrase
    • DNA polymerase
    • RNA polymerase
    • Reverse transcriptase
  10. Which type of microorganism causes tuberculosis, making it treatable with antibiotics?

    • Virus
    • Bacterium
    • Fungus
    • Protozoan
  11. Which viral structure undergoes rapid mutation, helping HIV evade immune recognition?

    • Capsid proteins
    • Reverse transcriptase
    • Envelope glycoproteins
    • Lipid membrane
  12. Which cells are destroyed by HIV, leading to a severely weakened immune system?

    • Cytotoxic T cells
    • Helper T cells
    • Phagocytes
    • B lymphocytes
  13. Where do tuberculosis bacteria survive inside the host to evade initial immune destruction?

    • Epithelial cells
    • Macrophages
    • Red blood cells
    • B cells
  14. By which process do new HIV particles leave an infected host cell?

    • Budding
    • Endocytosis
    • Exocytosis
    • Lysis
  15. How is HIV primarily transmitted from person to person?

    • Direct fluid exchange
    • Contaminated water
    • Vector bites
    • Airborne droplets
  16. Which enzyme incorporates viral DNA into the host cell's genome during HIV infection?

    • Reverse transcriptase
    • Integrase
    • DNA ligase
    • RNA polymerase
  17. Which lung cells ingest Mycobacterium tuberculosis but fail to destroy the pathogen?

    • Alveolar macrophages
    • Goblet cells
    • Red blood cells
    • Ciliated epithelial cells
  18. What is the final stage of untreated HIV infection, characterised by severe immunodeficiency?

    • Primary infection
    • Clinical latency
    • Acute infection
    • AIDS
  19. How many HIV particles are produced by 50 cells producing 10 particles daily over 3 days?

    • 4,500
    • 1,500
    • 150
    • 500
  20. Which diagnostic test confirms active pulmonary tuberculosis rather than a latent infection?

    • Chest X-ray
    • Blood antibody test
    • Sputum culture
    • Skin prick test

All Pearson Edexcel Biology quizzes